Hellhounds only appear a few times, but are very dangerous. They often attack in packs and can leap great distances, slashing with devastating claw swipes. They are also very durable and can take a lot of ammo to put down. Fortunately they give away their position by growling right before attacking.
Hellhounds lunge often and can easily cause a quick death by attacking in packs. It is best to continuously roll until distance is made between a Hellhound. The strongest weapon available in the inventory should be used against them to put them away quick, as they can take away health with great speed.